Investigation of the role of ACTN3 rs1815739 gene polymorphic variants on-field playing positions and genotype distributions in elite level male soccer players

Mon, 03 Mar 2025 00:00:00 +0000

The alpha-actinin-3 (ACTN3) gene, which encodes the sarcomeric protein alpha-actinin-3 in skeletal muscle fibers, is a significant marker linked to athletic performance. The distribution of ACTN3 gene alleles and genotypes between top athletes and sedentary individuals may result in substantial disparities in the development of physical performance attributes, including strength, speed, and endurance. This study sought to investigate the influence of ACTN3 rs1815739 gene polymorphisms in elite male soccer players concerning their on-field positions and to ascertain their genotype distributions. The research population comprises 78 male soccer players participating in professional leagues. The genotype distributions of the ACTN3 rs1815739 polymorphism among soccer players are as follows: CC genotype 34.62%, CT genotype 48.72%, and TT genotype 16.67%. The study revealed that professional soccer players with the TT genotype were present at a significantly low frequency in the general population. The distribution of ACTN3 gene polymorphisms exhibited a linear trend: CT>CC>TT. Additionally, no correlation was identified between the players' positions on the field and their gene polymorphisms. Consequently, ACTN3 R577X is considered an inadequate genetic marker for identifying a skilled soccer player, particularly when technical, tactical, and personal competencies that influence game outcomes are overlooked.

Public Knowledge, Attitudes, and Willingness to Use Genetically Modified Foods in Ogun State, Nigeria

Olusegun Emmanuel Ogundele, Folasade Tinuade Ojo, Adebola Daniel Awofodu — Wed, 14 May 2025 00:00:00 +0000

The increasing focus on genetically modified (GM) foods has sparked significant debate, particularly in developing countries like Nigeria, where food security remains a pressing issue. This study aims to assess public knowledge, attitudes, and willingness to use GM foods in Ogun State, Nigeria, in light of the federal government's endorsement of some GM crops to enhance agricultural productivity and nutritional quality. A descriptive survey design was employed, targeting adults aged 18 years and above across four divisions of Ogun State: Ijebu, Egba, Remo, and Yewa. A total of 1,104 participants were selected using stratified random sampling. Data were collected through a structured questionnaire designed to evaluate knowledge, attitudes, and willingness regarding GM foods. The findings indicate that 70.9% of respondents had heard of GM foods, but only 39% accurately distinguished them from hybrids. Willingness to purchase GM foods was high, particularly among those who perceived them as healthier or more affordable. Regional differences were observed, with participants from Remo exhibiting the highest acceptance levels. Concerns regarding health risks and environmental impacts were prevalent, highlighting the need for targeted educational initiatives to address misconceptions and improve public understanding. This study provides insights into the perceptions of GM foods in Ogun State, emphasising the importance of education in fostering acceptance. It appears that while there is general willingness to adopt GM foods, significant knowledge gaps and persistent misconceptions must be addressed to facilitate informed decision-making and support the integration of GM technologies into sustainable agricultural practices.

Genetics & Applications

Investigation of the role of ACTN3 rs1815739 gene polymorphic variants on-field playing positions and genotype distributions in elite level male soccer players

Public Knowledge, Attitudes, and Willingness to Use Genetically Modified Foods in Ogun State, Nigeria