https://genapp.ba/editions/index.php/journal <p><strong>Genetics &amp; Applications</strong> (G&amp;A) is the official journal of the Institute for Genetic Engineering and Biotechnology (<a title="INGEB" href="http://www.ingeb.unsa.ba" target="_blank" rel="noopener">www.ingeb.unsa.ba</a>), University of Sarajevo (<a href="http://www.unsa.ba/">http://www.unsa.ba/</a>). It is envisaged as an open access international journal issued twice a year in print and electronic (online) format, publishing peer-reviewed articles of novel and significant discoveries in the fields of basic and applied genetics. Special issues or supplements may also be produced from time to time upon agreement with the Editorial Board.</p> <p>Topics covered within Genetics and Applications (G&amp;A) include: </p> <p>Molecular genetics, Cytogenetics, Plant genetics, Animal genetics, Human genetics, Medical genetics, Forensic genetics, Population and evolutionary genetics, Conservation genetics, Genomics and functional genomics, Genetic engineering and biotechnology and Bioinformatics.</p> <p>Authors are encouraged to submit complete, unpublished, original works that are not under review in any other journals. Acceptable papers are those that gather and disseminate fundamental knowledge in all areas of genetics.</p> Institute for Genetic Engineering and Biotechnology, University of Sarajevo en-US Genetics & Applications 2566-2937 <p><a href="http://creativecommons.org/licenses/by-sa/4.0/" rel="license"><img style="border-width: 0;" src="https://i.creativecommons.org/l/by-sa/4.0/88x31.png" alt="Creative Commons License" /></a><br />This work is licensed under a <a href="http://creativecommons.org/licenses/by-sa/4.0/" rel="license">Creative Commons Attribution-ShareAlike 4.0 International License</a>.</p> <p>^©Genetics &amp; Applications, The Official Publication of the Institute for Genetic Engineering and Biotechnology, University of Sarajevo</p> https://genapp.ba/editions/index.php/journal/article/view/229 <p>The alpha-actinin-3 (ACTN3) gene, which encodes the sarcomeric protein alpha-actinin-3 in skeletal muscle fibers, is a significant marker linked to athletic performance. The distribution of ACTN3 gene alleles and genotypes between top athletes and sedentary individuals may result in substantial disparities in the development of physical performance attributes, including strength, speed, and endurance. This study sought to investigate the influence of ACTN3 rs1815739 gene polymorphisms in elite male soccer players concerning their on-field positions and to ascertain their genotype distributions. The research population comprises 78 male soccer players participating in professional leagues. The genotype distributions of the ACTN3 rs1815739 polymorphism among soccer players are as follows: CC genotype 34.62%, CT genotype 48.72%, and TT genotype 16.67%. The study revealed that professional soccer players with the TT genotype were present at a significantly low frequency in the general population. The distribution of ACTN3 gene polymorphisms exhibited a linear trend: CT&gt;CC&gt;TT. Additionally, no correlation was identified between the players' positions on the field and their gene polymorphisms. Consequently, ACTN3 R577X is considered an inadequate genetic marker for identifying a skilled soccer player, particularly when technical, tactical, and personal competencies that influence game outcomes are overlooked.</p> Murat Batuhan Şerolar Mesut Cerit Selin Yıldırım Tuncer Murat Anılır İrem Çatalo Tolga Polat Copyright (c) 2025 Genetics & Applications https://creativecommons.org/licenses/by-nc-sa/4.0 2025-03-03 2025-03-03 9 1 10.31383/ga.vol9iss1ga01